I ran across an interesting fact today: on average, a man’s skin is about 25% thicker than a woman’s skin.
Recently I have gained a first-hand (pun intended) understanding of life with thinner skin. A virus I had caused me to get hives on my hands. Then a week later, the skin started to peel off. So, I was down a layer of skin, and what was now exposed was far more sensitive than usual. I have cut myself doing things that normally would not be a problem, I get splinters left and right when I handle firewood, and the water seems a lot hotter when I wash dishes. I will forever be more understanding of the reality of my wife having thinner skin than I have.
Another common difference between men and women is that the average adult man has 50% more muscle than the average woman. Odds are he is stronger than you are, especially with regards to upper body strength.
You are probably aware of these differences, because you see him doing things you cannot, or easily doing things that would be a struggle for you. He may not be aware of your “limitations” in these areas, or he may chalk them up to “acting like a girl.” So share the facts with him and maybe he will give you a break.